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Place tablets in an appropriately sized amber bottle.
Add purified water to amber bottle and shake bottle for 2 minutes.
Let solution stand for 1 hour and then shake for 1 minute to disperse the tablet contents.
Add 114 mL of vehicle and shake well for 1 minute to disperse contents.
Special Instructions — *Mix 60 mL of Ora-Plus with 60 mL of Ora-Sweet SF. Use mixture as vehicle or use Ora-Blend SF.
Quality-Control Procedures — Visually inspect for physical appearance of formulation and container closure integrity (no leakage, cracks in container, or improper seals).
Labeling Requirements — Extemporaneously compounded preparation. For oral use only. Store in refrigerator. Shake well before use.
Storage Conditions/Stability — Refrigerate. Stable for 28 days.
Study Container Type — Amber polyethylene terephthalate (PET) bottle
Referenced Manufacturers — Losartan tablets (Cozaar, Merck & Co); Ora-Plus, Ora-Sweet SF (Paddock Laboratories, LLC).
Stability-Indicating Study — No
Cozaar [prescribing information]. Whitehouse Station, NJ: Merck & Co; 2019.
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