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Place tablets in an appropriately sized amber bottle.
Add purified water in amber bottle and shake bottle for 1 minute.
Add Bicitra in amber bottle and shake bottle again.
Add 96 mL Ora-Sweet NF and shake well to disperse contents.
Quality-Control Procedures — Visually inspect for physical appearance of formulation and container closure integrity (no leakage, cracks in container, or improper seals).
Labeling Requirements — Extemporaneously compounded preparation. For oral use only. Store at room temperature. Shake well before use.
Storage Conditions/Stability — Store at room temperature. Stable for 28 days.
Study Container Type — Amber polyethylene terephthalate (PET) bottle
Referenced Manufacturers — Lisinopril tablets (Prinivil, Merck & Co; Zestril, AstraZeneca), purified water (not specified); Bicitra (Alza Corp); Ora-Sweet SF (Paddock Laboratories, LLC).
Stability-Indicating Study — No
Commercially available — Use extemporaneously prepared formulation only when commercial product is unavailable.
Thompson KC, Zhao Z, Mazakas JM, et al.Characterization of an extemporaneous liquid formulation of lisinopril. Am J Health Syst Pharm. 2003;60:69–74.
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