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Powder containment hood, 2 × 18-G needles, 2 × 10-mL syringes, graduated cylinder
Reconstitute each vial of injectable powder with 10 mL of sterile water for injection.
Withdraw the contents from each vial into a syringe.
Transfer the solution to a graduated cylinder.
Add vehicle to the graduated cylinder to achieve the total volume indicated above.
Transfer contents of the graduated cylinder into an appropriately sized amber bottle.
Shake well to mix.
Quality-Control Procedures — Visually inspect for physical appearance of formulation and container closure integrity (no leakage, cracks in container, or improper seals).
Labeling Requirements — Extemporaneously compounded preparation. For oral use only. Store at room temperature. Shake well before use.
Storage Conditions/Stability — Store at room temperature. Stable for 56 days.
Study Container Type — Plastic prescription bottle
Referenced Manufacturers — Rifampin injection (Rifadin, Marion Merrell Dow); simple syrup (Humco); sterile water for injection (not specified).
Stability-Indicating Study — No
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