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Powder containment hood, 4 × 18-G needles, 2 × 10-mL syringes, 2 × 50-mL syringes
Measure out acetylcysteine solution and bacteriostatic sodium chloride 0.9% injection and place into appropriately sized amber bottle.
Shake well to mix.
Quality-Control Procedures — Visually inspect for physical appearance of formulation and container closure integrity (no leakage, cracks in container, or improper seals).
Labeling Requirements — Extemporaneously compounded preparation. For oral use only. Store at room temperature. Shake well before use.
Storage Conditions/Stability — Store at room temperature. Stable for 60 days.
Study Container Type — Amber plastic prescription bottle with child-resistant cap
Referenced Manufacturer — Acetylcysteine solution, bacteriostatic sodium chloride injection (Hospira).
Stability-Indicating Study — Yes
Fohl AL, Johnson CE, Cober MP. Stability of extemporaneously prepared acetylcysteine 1% and 10% solutions for treatment of meconium ileus. Am J Health Syst Pharm. 2011;68(1):69–72.
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