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Powder containment hood, graduated cylinder
Measure 25 mL of potassium chloride injection and add to a graduated cylinder.
Add vehicle to the graduated cylinder to achieve the total volume indicated above.
Transfer contents of the graduated cylinder into an appropriately sized amber bottle.
Shake well to mix.
Quality-Control Procedures — Visually inspect for physical appearance of formulation and container closure integrity (no leakage, cracks in container, or improper seals).
Labeling Requirements — Extemporaneously compounded preparation. For oral use only. Store in refrigerator. Shake well before use.
Storage Conditions/Stability — Refrigerate. Stable for 28 days.
Study Container Type — Amber glass bottle
Referenced Manufacturers — Potassium chloride injection (B. Braun Medical, Inc); Ora-Sweet SF (Perrigo Co).
Stability-Indicating Study — No
Commercially available as a 1.33- and 2.67-mEq/mL solution — Use extemporaneously prepared formulation only when commercial product is unavailable or a more dilute syrup is desired.
Tannous E, Tal Y, Amarny K. A simplified extemporaneously prepared potassium chloride oral solution. Int J Pharm Compd. 2016;20(5):438–439.
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