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Powder containment hood, mortar and pestle, beaker, magnetic stirrer, graduated cylinder
Remove imprint from tablets by gently rubbing with a paper towel dampened with ethanol.
Allow tablets to air-dry for a few minutes.
Triturate tablets to a fine powder with a mortar and pestle.
Transfer the contents of the mortar to an appropriately sized beaker.
Add vehicle to the beaker to achieve the total volume indicated above.
Place the beaker on a magnetic stirrer and stir for 30 minutes.
Transfer solution into an appropriately sized amber bottle.
Shake well to mix.
Quality-Control Procedures — Visually inspect for physical appearance of formulation and container closure integrity (no leakage, cracks in container, or improper seals).
Labeling Requirements — Extemporaneously compounded preparation. For oral use only. Store at room temperature or refrigerate. Shake well before use.
Storage Conditions/Stability — Store at room temperature or refrigerate. Stable for 14 days when refrigerated, 24 hours when stored at room temperature, and 90 days when stored at −20°C.
Study Container Type — 20-mL polypropylene syringe
Referenced Manufacturer — Not specified.
Stability-Indicating Study — No
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